Onder andere met: Ben Stiller (Derek Zoolander), Owen Wilson (Hansel), Christine Taylor (Matilda Jeffries), Will Ferrell (Mugatu), Milla Jovovich (Katinka), Jerry Stiller (Maury Ballstein), David Duchovny (J.P. Prewitt), Jon Voight (Larry Zoolander), Judah Friedlander (Scrappy Zoolander), Nathan Lee Graham (Todd), Alexandre Manning (Brint), Asio Highsmith (Rufus), Alexander Skarsgård (Meekus), Donald Trump (Himself), Christian Slater (Himself), Tommy Hilfiger (Himself), Lenny Kravitz (Himself)