Onder andere met: Christopher Walken (Dr. Michael Anthony Brace), Natalie Wood (Karen Brace), Louise Fletcher (Dr. Lillian Reynolds), Cliff Robertson (Alex Terson), Jordan Christopher (Gordy Forbes), Donald Hotton (Landan Marks), Alan Fudge (Robert Jenkins), Joe Dorsey (Hal Abramson), Bill Morey (James Zimbach), Jason Lively (Chris Brace), Darrell Larson (Security technician), Lou Walker (Chief), Stacey Kuhne-Adams (Andrea), John Hugh (Animal lab technician), Ira David Wood III (Barry (as David Wood))