Onder andere met: Milla Jovovich (Alice), Michelle Rodriguez (Rain Ocampo), Eric Mabius (Matt Addison), James Purefoy (Spence Parks), Martin Crewes (Chad Kaplan), Colin Salmon (One), Ryan McCluskey (Mr. Grey), Oscar Pearce (Mr. Red), Indra Ové (Ms. Black), Anna Bolt (Dr. Anna Bolt), Joseph May (Dr. Blue), Robert Tannion (Dr. Brown), Heike Makatsch (Dr. Lisa Addison), Jaymes Butler (Clarence the Security Guard), Stephen Billington (Mr. White),