Onder andere met: George Clooney (Capt. Billy Tyne), Mark Wahlberg (Bobby Shatford), Diane Lane (Christina `Chris` Cotter), John C. Reilly (Dale `Murph` Murphy), William Fichtner (David `Sully` Sullivan), Bob Gunton (Alexander McAnally III, Mistral Owner), Karen Allen (Melissa Brown), Mary Elizabeth Mastrantonio (Linda Greenlaw), Allen Payne (Alfred Pierre), John Hawkes (Mike `Bugsy` Moran), Christopher McDonald (Todd Gross, TV Meteorologist), Dash Mihok (Sgt. Jeremy Mitchell), Josh Hopkins (Capt. Daryl Ennis), Michael Ironside (Bob Brown), Cherry Jones (Edie Bailey),