Onder andere met: Adrien Brody (Jack Starks), Keira Knightley (Jackie Price), Kris Kristofferson (Dr. Thomas Becker), Jennifer Jason Leigh (Dr. Lorenson), Kelly Lynch (Jean Price), Brad Renfro (The Stranger), Daniel Craig (Rudy Mackenzie), Steven Mackintosh (Dr. Hopkins), Brendan Coyle (Damon), Mackenzie Phillips (Nurse Harding), Laura Marano (Young Jackie), Jason Lewis (Officer Harrison), Richard Dillane (Captain Medley), Jonah Lotan (Intern #1), Angel Coulby (Intern #2),