Onder andere met: Ioan Gruffudd (Reed Richards), Jessica Alba (Sue Storm), Chris Evans (Johnny Storm), Michael Chiklis (Ben Grimm), Julian McMahon (Victor Von Doom), Hamish Linklater (Leonard), Kerry Washington (Alicia Masters), Laurie Holden (Debbie McIlvane), David Parker (Ernie), Kevin McNulty (Jimmy O`Hoolihan), Maria Menounos (Sexy Nurse), Michael Kopsa (Ned Cecil), Andrew Airlie (Compound Doctor), Pascale Hutton (Nightclub Girlfriend), G. Michael Gray (Nightclub Boyfriend)