Onder andere met: Robert Downey Jr. (Dan Dark), Robin Wright Penn (Nicola/Nina/Blonde), Mel Gibson (Dr. Gibbon), Jeremy Northam (Mark Binney), Katie Holmes (Nurse Mills), Adrien Brody (First Hood), Jon Polito (Second Hood), Carla Gugino (Betty Dark/Hooker), Saul Rubinek (Skin Specialist), Alfre Woodard (Chief of Staff), Amy Aquino (Nurse Nozhki), David Dorfman (Young Dan Dark), Eddie Jones (Moonglow Bartender), Lily Knight (Woman Physiotherapist), Clyde Kusatsu (Visiting Japanese Doctor)