Onder andere met: Frances McDormand (Mildred Hayes), Woody Harrelson (Willoughby), Sam Rockwell (Dixon), Sandy Martin (Mevrouw Dixon), Caleb Landry Jones (Red Welby), Nick Searcy (Father Montgomery), Lucas Hedges (Robbie), John Hawkes (Charlie), Abbie Cornish (Anne Willoughby), Kerry Condon (Pamela), Kathryn Newton (Angela), Amanda Warren (Denise Watson), Darrell Britt-Gibson (Jerome), Malaya Drew (Gabriella Forrester), Clarke peters (Abercrombie), Alejandro Barrios (Verdachte)