Onder andere met: Seth Rogen (Mac Radner), Rose Byrne (Kelly Radner), Zac Efron (Teddy Sanders), Chloë Grace Moretz (Shelby), Ike Barinholtz (Jimmy), Kiersey Clemons (Beth), Dave Franco (Pete), Jerrod Carmichael (Garf), Christopher Mintz-Plasse (Scoonie), Beanie Feldstein (Nora), Clara Mamet (Maranda), Awkwafina (Christine), Selena Gomez (Phi Lambda President), Hannibal Buress (Officer Watkins), Elise Vargas (Stella), Zoey Vargas (Stella), Carla Gallo (Paula), John Early (Darren)