Onder andere met: Ben Stiller (Derek), Owen Wilson (Hansel), Will Ferrell (Jacobim Mugatu), Penélope Cruz (Valentina Valencia), Milla Jovovich (Katinka), Jon Daly (Agent Filippo), Christine Taylor (Matilda), Justin Theroux (Evil DJ), Jerry Stiller (Maury), Kristen Wiig (Alexanya Atoz), Jourdan Dunn (Natalka), Kyle Mooney (Don Atari), Benedict Cumberbatch (All), Gionata Curreri (Fabrizio), Christina Hendricks (Seductress), Ariana Grande (Latex BDSM), Alexander Skarsgård (Adam), Karlie Kloss (Eve), Nathan Lee Graham (Todd), Justin Bieber (Himself), Katie Couric (Herself), Kiefer Sutherland (Himself), Susan Boyle (Herself), M.C. Hammer (Himself), Naomi Campbell (Herself), Katy Perry (Herself)