Onder andere met: Miles Teller (Reed Richards), Michael B. Jordan (Johnny Storm), Kate Mara (Sue Storm), Jamie Bell (Ben Grimm / The Thing), Toby Kebbell (Victor Von Doom / Dr. Doom), Reg E. Cathey (Dr. Franklin Storm), Tim Blake Nelson (Dr. Allen), Dan Castellaneta (Mr. Kenny), Owen Judge (Young Reed), Evan Hannemann (Young Ben), Chet Hanks (Jimmy Grimm), Mary-Pat Green (Mrs. Grimm), Tim Heidecker (Mr. Richards), Mary Rachel Dudley (Mrs. Richards)