Onder andere met: Chris Pratt (Peter Quill), Zoe Saldana (Gamora), Dave Bautista (Drax), Vin Diesel (Groot (voice)), Bradley Cooper (Rocket (voice)), Lee Pace (Ronan), Michael Rooker (Yondu Udonta), Karen Gillan (Nebula), Djimon Hounsou (Korath), John C. Reilly (Corpsman Dey), Glenn Close (Nova Prime), Benicio Del Toro (The Collector), Laura Haddock (Meredith Quill), Sean Gunn (Kraglin), Peter Serafinowicz (Denarian Saal), Christopher Fairbank (The Broker), Robert Firth (Dr. Fitzgibbon), Melia Kreiling (Bereet), Tom Proctor (Horuz)