Onder andere met: Bill Murray (Steve Zissou), Owen Wilson (Ned Plimpton), Cate Blanchett (Jane Winslett-Richardson), Anjelica Huston (Eleanor Zissou), Willem Dafoe (Klaus Daimler), Jeff Goldblum (Alistair Hennessey), Michael Gambon (Oseary Drakoulias), Noah Taylor (Vladimir Wolodarsky), Bud Cort (Bill Ubell), Seu Jorge (Pelé dos Santos), Robyn Cohen (Anne-Marie Sakowitz), Waris Ahluwalia (Vikram Ray), Niels Koizumi (Bobby Ogata), Pawel Wdowczak (Renzo Pietro), Matthew Gray Gubler (Intern #1)

Topfert? Eh yeeeeeeeees!