Onder andere met: Antonio Banderas (Gregorio Cortez), Carla Gugino (Ingrid Cortez), Alexa Vega (Carmen Cortez), Daryl Sabara (Juni Cortez), Ricardo Montalban (Grandfather), Holland Taylor (Grandmother), Sylvester Stallone (Toymaker), Mike Judge (Donnagon Giggles), Salma Hayek (Cesca Giggles), Matt O`Leary (Gary Giggles), Emily Osment (Gerti Giggles), Cheech Marin (Felix Gumm), Danny Trejo (Machete), Steve Buscemi (Romero), Bill Paxton (Dinky Winks), George Clooney (Devlin), Elijah Wood (The Guy)