Onder andere met: Channing Tatum (Duke), Adewale Akinnuoye-Agbaje (Heavy Duty), Christopher Eccleston (McCullen / Destro), Joseph Gordon-Levitt (The Doctor / Rex), Grégory Fitoussi (Baron de Cobray), Sienna Miller (Ana / Baroness), Rachel Nichols (Scarlett), Kevin J. O'Connor (Dr. Mindbender), Ray Park (Snake Eyes), Jonathan Pryce (U.S. President), Dennis Quaid (General Hawk), Karolina Kurkova (Cover Girl), Saïd Taghmaoui (Breaker), Arnold Vosloo (Zartan), Marlon Wayans (Ripcord), Peter Breitmayer (Dr. Hundtkinder), Liana Mendoza (Lt. Girlfriend), Leo Howard (Young Snake Eyes), Gerald Okamura (Hard Master)