Onder andere met: Arnold Schwarzenegger (Quaid/Hauser), Rachel Ticotin (Melina), Sharon Stone ( Lori Quaid), Ronny Cox (Vilos Cohaagen), Michael Ironside (Richter, . Mel Johnson Cohaagen's chief lieutenant), Jr. (Benny, a taxi driver), Marshall Bell . Roy Brocksmith (George/Voice of Kuato)(Dr. Edgemar), Ray Baker (Bob McClane), Michael Champion (Helm, Richter's acerbic right hand man), Rosemary Dunsmore (Dr. Renata Lull), Robert Costanzo (Harry), Marc Alaimo (Everett), Dean Norris (Tony, a disfigured mutant), Lycia Naff (Mary, . widely-known as the Three-Breasted prostitute)