Onder andere met: Johnny Depp (Commander Spencer Armacost), Charlize Theron (Jillian Armacost), Joe Morton (Sherman Reese, NASA Representative), Clea DuVall (Nan), Donna Murphy (Natalie Streck), Nick Cassavetes (Capt. Alex Streck), Samantha Eggar (Dr. Patraba), Gary Grubbs (NASA Director), Blair Brown (Shelly McLaren), Tom Noonan (Jackson McLaren), Tom O'Brien (Allen Dodge), Lucy Lin (Shelly Carter), Michael Crider (Pat Elliott), Jacob Stein (Calvin), Sarah Dampf (Paula), Rondi Reed (Dr. Conlin),