Onder andere met: Christopher Lambert (Connor 'The Highlander' MacLeod / Russell Edwin Nash), Roxanne Hart (Brenda J. Wyatt), Clancy Brown (Victor Kruger / The Kurgan), Sean Connery (Juan Sanchez Villa-Lobos Ramirez), Beatie Edney (Heather MacLeod), Alan North (Lieutenant Frank Moran), Jon Polito (Det. Walter Bedsoe), Sheila Gish (Rachel Ellenstein), Hugh Quarshie (Sunda Kastagir), Christopher Malcolm (Kirk Matunas), Peter Diamond (Aman Fasil), Billy Hartman (Dugal MacLeod), James Cosmo (Angus MacLeod), Celia Imrie (Kate MacLeod), Alistair Findlay (Chief Murdoch), Edward Wiley (Garfield), James McKenna (Father Rainey), John Cassady (Kenny)