Onder andere met: Tobin Bell (Jigsaw / John Kramer), Costas Mandylor (Det. Mark Hoffman), Betsy Russell (Jill Tuck), Cary Elwes (Dr. Lawrence Gordon), Sean Patrick Flanery (Bobby Dagen), Chad Donella (Det. Matt Gibson), Gina Holden (Joyce Dagen), Laurence Anthony (Det. Rogers), Dean Armstrong (Cale), Naomi Snieckus (Nina), Rebecca Marshall (Suzanne), James Van Patten (Dr. Heffner), Sebastian Pigott (Brad), Jon Cor (Ryan), Anne Lee Greene (Dina)