Onder andere met: Clark Gable (Edward J. 'Blackie' Gallagher), William Powell (Jim Wade), Myrna Loy (Eleanor Packer), Leo Carrillo (Father Joe), Nat Pendleton (Spud), George Sidney (Poppa Rosen), Isabel Jewell (Annabelle), Muriel Evans (Tootsie Malone), Thomas E. Jackson (Richard Snow), Isabelle Keith (Miss Adams), Frank Conroy (Blackie's Defense Attorney), Noel Madison (Manny Arnold), Jimmy Butler (Jim Wade as a Boy), Mickey Rooney (Blackie as a Boy), Shirley Ross (Singer in Cotton Club)