Onder andere met: Bruce Willis (Lieutenant John McClane), William Sadler (Colonel Stuart), Art Evans (Leslie Barnes), Dennis Franz (Captain Carmine Lorenzo), Reginald VelJohnson (Sergeant Al Powell), William Atherton (Richard "Dick" Thornberg), Franco Nero (General Ramon Esperanza), John Amos (Major Grant), Bonnie Bedelia (Holly Gennero McClane), Fred Thompson (Trudeau), Tom Bower (Marvin), Sheila McCarthy (Samantha "Sam" Coleman), Robert Patrick (O'Reilly), John Leguizamo (Burke)