Onder andere met: Paul Reubens (Pee-wee Herman), Elizabeth Daily (Dottie), Mark Holton (Francis Buxton), Diane Salinger (Simone), Judd Omen (Mickey), Irving Hellman (Mr. Crowtray), Monte Landis (Mario), Damon Martin (Chip), David Glasser (BMX Kid), Gregory Brown (BMX Kid), Mark Everett (BMX Kid), Daryl Keith Roach (Chuck), Bill Cable (Policeman #1), Peter Looney (Policeman #2), Starletta DuPois (Sgt. Hunter), Ed Herlihy (Mr. Buxton), Lou Cutell (Amazing Larry), Alice Nunn (Large Marge), Cassandra Peterson (Biker Mama)