Onder andere met: Jonah Hill (Seth), Michael Cera (Evan), Christopher Mintz-Plasse (Fogell), Bill Hader (Officer Slater), Seth Rogen (Officer Michaels), Martha MacIsaac (Becca), Emma Stone (Jules), Aviva (Nicola), Joe Lo Truglio (Francis the Driver), Kevin Corrigan (Mark), Clement Blake (Homeless Guy), Erica Vittina Phillips (Liquor Store Cashier), Joe Nunez (Liquor Store Clerk), Dave Franco (Greg the Soccer Player), Marcella Lentz-Pope (Gaby), Carla Gallo (Period Blood Girl), Matthew Bass (Vagtastic Voyager), Aurora Snow (Vagtastic Voyage Girl), Jenna Haze (Vagtastic Voyage Girl), Carrie Keagan (Party Girl), Jill Maddrell (Party Guest)