Onder andere met: Jeff Fahey (Peter Rooker), Arnold Vosloo (Darkman / Dr. Peyton Westlake), Darlanne Fluegel (Dr. Bridget Thorne), Roxann Dawson (Angela Rooker), Nigel Bennett (Nico), Alicia Panetta (Jenny Rooker), Ronn Sarosiak (Mack), Peter Graham (Joey), Shawn Doyle (Adam), Vieslav Krystyan (Ivan), Chris Adams (Whit), Rick Parker (E.K.), Joel Bissonnette (Mayo), John Novak (Dist. Atty. Ryan Mitchell), Christopher Bondy (Gibson)