Onder andere met: Nicolas Cage (Ben Gates), Justin Bartha (Riley Poole), Diane Kruger (Abigail Chase), Jon Voight (Patrick Gates), Helen Mirren (Emily Appleton), Ed Harris (Mitch Wilkinson), Harvey Keitel (Sadusky), Bruce Greenwood (The President), Ty Burrell (Connor), Michael Maize (Daniel), Timothy V. Murphy (Seth), Alicia Coppola (FBI Agent Spellman), Armando Riesco (FBI Agent Hendricks), Albert Hall (Dr. Nichols), Joel Gretsch (Thomas Gates)