Onder andere met: Anthony Perkins (Norman Bates), Janet Leigh (Marion Crane), Vera Miles (Lila Crane), John Gavin (Sam Loomis), Martin Balsam (Milton Arbogast), John McIntire (Deputy Sheriff Al Chambers), Simon Oakland (Dr. Fred Richmond), Vaughn Taylor (George Lowery, realtor), Frank Albertson (Tom Cassidy, home buyer), Lurene Tuttle (Eliza Chambers), Patricia Hitchcock (Caroline (as Pat Hitchcock)), John Anderson (Charlie, used car salesman), Mort Mills (Highway Patrol officer)