Onder andere met: Helen Hunt (Dr. JoAnne `Jo` Thornton-Harding), Bill Paxton (William Harding), Cary Elwes (Dr. Jonas Miller), Jami Gertz (Dr. Melissa Reeves), Philip Seymour Hoffman (Dustin Davis), Lois Smith (Meg Greene), Alan Ruck (Robert `Rabbit` Nurick), Sean Whalen (Allan Sanders), Scott Thomson (Jason `Preacher` Rowe), Todd Field (Tim `Beltzer` Lewis), Joey Slotnick (Joey), Wendle Josepher (Haynes), Jeremy Davies (Laurence), Zach Grenier (Eddie), Gregory Sporleder (Willie)