Onder andere met: Johnny Depp (John Dillinger), Christian Bale (Melvin Purvis), Marion Cotillard (Billie Frechette), James Russo (Walter Dietrich), David Wenham (Harry 'Pete' Pierpont), Christian Stolte (Charles Makley), Jason Clarke (John 'Red' Hamilton), John Judd (Turnkey), Stephen Dorff (Homer Van Meter), Michael Vieau (Ed Shouse), John Kishline (Guard Dainard), Wesley Walker (Jim Leslie), John Scherp (Earl Adams), Elena Kenney (Viola Norris), William Nero Jr. (Farm boy), Channing Tatum (Pretty Boy Floyd), Rory Cochrane (Agent Carter Baum)