Onder andere met: Halle Berry (Miranda Grey), Robert Downey Jr. (Pete Graham), Charles Dutton (Dr. Douglas Grey (as Charles S. Dutton)), John Carroll Lynch (Sheriff Ryan), Bernard Hill (Phil Parsons), Penélope Cruz (Chloe Sava), Dorian Harewood (Teddy Howard), Bronwen Mantel (Irene), Kathleen Mackey (Rachel Parsons), Matthew G. Taylor (Turlington), Michel Perron (Joe), Andrea Sheldon (Tracey Seavers), Anana Rydvald (Glass Cell Nurse), Laura Mitchell en Amy Sloan (Inmate)(Inmate)