Onder andere met: Robert Downey Jr. (Tony Stark), Terrence Howard (Rhodey), Jeff Bridges (Obadiah Stane), Gwyneth Paltrow (Pepper Potts), Leslie Bibb (Christine Everhart), Shaun Toub (Yinsen), Faran Tahir (Raza), Clark Gregg (Agent Coulson), Bill Smitrovich (General Gabriel), Sayed Badreya (Abu Bakaar), Paul Bettany (Jarvis (Voice)), Jon Favreau (Hogan), Peter Billingsley (William Ginter Riva), Tim Guinee (Major Allen)