Onder andere met: Keir Dullea (Dr. Dave Bowman), Gary Lockwood (Dr. Frank Poole), William Sylvester (Dr. Heywood R. Floyd), Daniel Richter (Moonwatcher), Leonard Rossiter (Dr. Andrei Smyslov), Margaret Tyzack (Elena), Robert Beatty (Dr. Rolf Halvorsen), Sean Sullivan (Dr. Bill Michaels), Douglas Rain (HAL 9000 (voice)), Frank Miller (Mission controller (voice)), Bill Weston (Astronaut), Ed Bishop (Aries 1B Lunar shuttle captain (as Edward Bishop)), Glenn Beck (Astronaut), Alan Gifford (Poole`s father), Ann Gillis (Poole`s mother)

Slowest movie everrrr...