Onder andere met: Carlos Alazraqui (Nestor (voice)), Lombardo Boyar (Raul (voice)), Jeffrey Garcia (Rinaldo (voice) (as Jeff Garcia)), Johnny A. Sanchez (Lombardo (voice) (as Johnny Sanchez III)), Robin Williams (Ramon/Lovelace (voice)), Elijah Wood (Mumble (voice)), Brittany Murphy (Gloria (voice)), Hugh Jackman (Memphis (voice)), Nicole Kidman (Norma Jean (voice)), Hugo Weaving (Noah the Elder (voice)), Elizabeth Daily (Baby Mumble (voice) (as E.G. Daily)), Magda Szubanski (Miss Viola (voice)), Miriam Margolyes (Mrs. Astrakhan (voice)), Fat Joe (Seymour (voice)), Alyssa Shafer (Baby Gloria (voice))