Onder andere met: Tom Cruise (Ethan Hunt), Jon Voight (Jim Phelps), Emmanuelle Béart (Claire Phelps (as Emmanuelle Beart)), Henry Czerny (Eugene Kittridge), Jean Reno (Franz Krieger), Ving Rhames (Luther Stickell), Kristin Scott Thomas (Sarah Davies (as Kristin Scott-Thomas)), Vanessa Redgrave (Max), Dale Dye (Frank Barnes), Marcel Iures (Alexander Golitsyn), Ion Caramitru (Zozimov), Ingeborga Dapkunaite (Hannah Williams), Valentina Yakunina (Drunken Female IMF Agent), Marek Vasut (Drunken Male IMF Agent), Nathan Osgood (Kittridge Technician)