Onder andere met: Robert De Niro (The Creature), Kenneth Branagh (Victor Frankenstein), Tom Hulce (Henry Clerval), Helena Bonham Carter (Elizabeth), Aidan Quinn (Captain Robert Walton), Ian Holm (Baron Frankenstein), Richard Briers (Grandfather), John Cleese (Professor Waldman), Robert Hardy (Professor Krempe), Cherie Lunghi (Victor`s Mother), Celia Imrie (Mrs. Moritz), Trevyn McDowell (Justine), Gerard Horan (Claude), Mark Hadfield (Felix), Joanna Roth (Marie)