Onder andere met: Hilary Swank (Brandon Teena), Chloë Sevigny (Lana Tisdel), Peter Sarsgaard (John Lotter), Brendan Sexton III (Tom Nissen), Alicia Goranson (Candace), Alison Folland (Kate), Jeanetta Arnette (Lana`s Mom (as Jeannetta Arnette)), Rob Campbell (Brian), Matt McGrath (Lonny), Cheyenne Rushing (Nicole), Robert Prentiss (Trucker), Josh Ridgway (Kwik Stop Cashier), Craig Erickson (Trucker in Kwik Stop), Stephanie Sechrist (April), Jerry Haynes (Judge),